alcohol
recovery
you.
naturally.
silymarin
feel better | perform better

ideal for

 

  •  the clean living, health concious over-indulger

     

  • relieving the symptoms associated with the over-indulgence of drink

 

 

what is silymarin?

  • silymarin is the active ingredience in milk thistle which is extracted from the seed of the plant.

 

  • "silymarin stimulates detoxification pathways and stimulates the regeneration of liver tissue"  US NIR National Cancer Institute, Complemetary Therapies Editorial Board 2003

our silymarin

 

    • silymarin is a compound found in milk thistle.

 

    • 400 mg of silymarin per tablet

 

  • 20 tablet pouch

 

  • alcohol is one of the best known toxins that damages the liver and large amounts creates extreme oxidative stress on liver tissue. Significant alcohol consumption produces accumulations of fat in liver cells, with small areas of dead tissue, accompanied by a rise in liver enzymes in the blood (from leaking, dying cells).
  • in a  study with healthy volunteers receiving single doses of either one (175mg), two (350mg) or 3 (475mg) of milk thistle capsules [1] it was found that biomarkers for oxidative stress were decreased in volunteers after 28 days. And, this effect was dose proportional [1].
  • silymarin is also thought to protect the brain due to the role it plays in protecting cells from oxidative stress. In the brain oxidative stress is caused by by-products of reactions involving oxygen and the breakdown of ethanol within the cell metabolism [2]
  • a study by Ferenci et al. demonstrated this in a placebo controlled trial of the use of silymarin in people with cirrhosis. A systematic review published in 2005 by Rambaldi et al. studied 13 randomised control trials and concluded that silymarin may increase the life expectancy of patients with liver disease [4]
  • lightweight, convenient eco-friendly foil packaging. Travel bag, wash bag, work bag friendly

 


 

 

Study Disease Silymarin Dosage (mg/day) Treatment Duration (days)  Results
Ferenci          [3] Chronic alcohol and other forms of liver disease 420 730 58% of patients increased life expectancy
Salmi            [5] Chronic alcohol liver disease 420 28 73% of patients improved
Palasciano    [6] Chronic drug-induced liver disease 800 90 Reduction in liver cell damage
Buzelli          [7] Chronic hepatitis 240 7 Reduction in liver cell damage

 


 

 [1] Zhu, H.-J., et al., An Assessment of Pharmacokinetics and Antioxidant Activity of Free Silymarin Flavonolignans in Healthy Volunteers: A Dose Escalation Study. Drug Metabolism and Disposition, 2013. 41(9): p. 1679-1685.  [2] Coyle, J.T. and P. Puttfarcken, Oxidative stress, glutamate, and neurodegenerative disorders. Science, 1993. 262(5134): p. 689-695.  [3] Ferenci, P., et al., Randomized controlled trial of silymarin treatment in patients with cirrhosis of the liver. Journal of Hepatology, 1989. 9(1): p. 105-113.   [4] Rambaldi, A., B.P. Jacobs, and C. Gluud, Milk thistle for alcoholic and/or hepatitis B or C virus liver diseases. Cochrane Database Syst Rev, 2007(4): p. Cd003620.  [5]  Salmi, H.A. and S. Sarna, Effect of Silymarin on Chemical, Functional, and Morphological  Alterations of the Liver. Scandinavian Journal of Gastroenterology, 1982. 17(4): p. 517-521.  [6] Palasciano, G., et al., The effect of silymarin on plasma levels of malon-dialdehyde in patients receiving long-term treatment with psychotropic drugs. Current Therapeutic Research, 1994. 55(5): p. 537-545.  [7] Buzzelli, G., et al., A pilot study on the liver protective effect of silybin-phosphatidylcholine complex (IdB1016) in chronic active hepatitis. Int J Clin Pharmacol Ther Toxicol, 1993. 31(9): p. 456-60.

 

    • take 1 tablet before you start drinking and 1 before bed.

 

    • 400 mg of silymarin in each tablet 

 

  • 20 tablet pouch

 

  • maximum 2 tablets per day

 

    • milk thistle seed extract

 

    • 400 mg of silymarin in each tablet 

 

  • tableting agent: microcrystalline cellulose

 

  • anti-caking agents: silicon dioxid & magnesium stearate

Availability: In stock

£19.99
£19.99 £19.99
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alcohol recovery

  • silymarin is a compound found in milk thistle

 

  • our 400mg strength tablets may be beneficial to people looking to relieve the symptoms associated with the occasional over-indulgence in drink

 

  • take 1 tablet before you start drinking and 1 before bed

What is milk thistle and how does it work?

SIlymarin - the compound found in milk thistle "stimulates detoxification pathways & the regeneration of liver tissue" *. Can this become your hangover cure?

Find out more

Ever wondered what alcohol does to your brain?

Alcohol can often lead to a somewhat drastic loss of inhibitions, causing some drinkers to be a little emotional, overindulgent, and uncharacteristically adventurous while under the influence.

Find out more

What is a hangover? The biological effects of your night out

Ever wondered why over-indulging in alcohol has to be so consequently painful the next morning? Most studies agree that hangovers are a result of a disruption to the balance of chemicals in your brain.

Find out more

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