Skip to content
Close (esc)


Use code NEW15 to save 15% on your 1st order. FREE UK next day delivery if you order before 3PM . FREE USA delivery 5-7 days.

Alpha gpc choline exercise

studies show Alpha GPC boosts workout performance

Published Jun 1, 2021 | Updated Jun 17, 2022

fitness enthusiast view growth hormones as a way to enhance workout performance. There are ways to encourage your body to naturally boost growth hormone production, such as combining exercise with some key nutrients.

could exercise boost hormone production for muscle mass?

growth hormones are naturally produced by a gland in the brain that acts as a messenger system in your body. This gland, also known as the pituitary gland, regulates body functions by releasing hormones, such as growth hormones, into the blood [1]. Growth hormones fuel childhood growth and are often released in bursts in response to exercise and sleep [2]. Exercise is a particularly potent stimulus for growth hormones production and has been shown to increase muscle mass [3].

if you are looking for an alternative way to elevate growth hormone levels, you may be interested in the clinical evidence of an isolated nutrient called Alpha GPC. A study published in the Journal of the International Society of Sports Nutrition showed that administering Alpha-GPC 90 minutes pre-weight training sessions increased growth hormone production and peak bench press force [4]. 200mg Alpha GPC has been shown to improve vertical jump peak power by 8.5%, increase endurance performance and growth hormone production [5].

alpha-gpc choline supplements exercise

what is Alpha GPC?

Alpha GPC is a potent form of choline that naturally occurs in the brain, and it is the building block of the chemical messenger called acetylcholine [6]. Acetylcholine is released when conducting cognitive tasks such as memory retention or learning [7].

research suggests Alpha GPC can also help prevent exercise-induced reductions in choline levels [5]. It has been shown to increase lower body force production after 6 days of supplementation [8] and could be recommended to athletes and coaches looking to improve performance in events focused on velocity and power [9].

why else should you be interested in Alpha GPC?

Alpha GPC has been shown to increase relative spikes of acetylcholine around 1-3 hours post-ingestion [10]. Increased concentration of acetylcholine has been shown to improve attention during sustained attention performance tasks in animal studies [11]. According to Pharmacology, Biochemistry and Behaviour, taking Alpha GPC for 20 days improved learning and memory capacity in rats with mild cognitive impairments [12]. Clinical evidence showed that amongst 2044 patients with mild cognitive impairment, a daily dose of Alpha GPC, 71% corresponded to "no cognitive decline" or "forgetfulness" [13].

how can you obtain Alpha GPC?

the richest sources of choline are found in animal proteins such as beef, liver and eggs [2]. Food-derived choline and other forms of choline, such as choline bitartrate, require complex mechanisms of action to enter the brain. Alternatively, you may prefer to supplement with Alpha GPC.

if you're looking for a vegan-friendly choline supplement, brain feed offers the world's first 99% 500 mg Alpha GPC capsule, served in a single capsule [14]. It is recommended that you take one per day, ideally in the morning, at lunch, or just before you start work. It is safe and regulated by the Good Manufacturing Practice (GMP) Medicines and Healthcare Products Regulatory Agency (MHRA).


[1]Patient Info (2018) Pituitary Gland disorders. [2]Ziesel et al. (2003) Concentrations of Choline-Containing Com-pounds and Betaine in Common Foods. The Journal of Nutrition. [3]Gilmore Health News (2020) Alpha GPC Stimulates The Production Of HGH During Exercise.  [4]Ziegenfuss et al. (2008) Acute supplementation with alpha-glycerylphosphorylcholine augments growth hormone response to, and peak force production during, resistance exercise. Journal of the international society of sports nutrition. [5]Parker et al. (2015) The effects of alpha-glycerylphosphorylcholine, caffeine or placebo on markers of mood, cognitive function, power, speed, and agility. Journal of the International Society of Sports Nutrition. [6]Zeisel et al. (1991) Choline, an essential nutrient for humans. [7]Hasselmo, M.E. (2006) The role of acetylcholine in learning and memory. Current opinion in neurobiology. [8]Beller et al. (2015). The effect of 6 days of alpha glycerylphosphorylcholine on isometric strength. Journal of the International Society of Sports Nutrition. [9]Marcus et al. (2017). Evaluation of the effects of two doses of alpha glycerylphosphorylcholine on physical and psychomotor performance. Journal of the International Society of Sports Nutrition[10]Examine (2018) Alpha GPC. [11]Himmelheber et al. (2000) Increases in cortical acetylcholine release during sustained attention performance in rats. Cognitive Brain Research. [12]Drago et al. (1992) Behavioral effects of L-α-glycerylphosphorylcholine: Influence on cognitive mechanisms in the rat. Pharmacology Biochemistry and Behavior. [13]Sangiorgi et al. (1994) α‐Glycerophosphocholine in the Mental Recovery of Cerebral Ischemic Attacks. Pharmacology of Aging Processes: Methods of Assessment and Potential Interventions. [14]Brain feed (2018) alpha GPC.

Leave a comment

Open tab

Please note, comments must be approved before they are published

Related articles

andrew huberman supplement list  andrew huberman supplementsandrew huberman recommended supplements l tyrosine huberman andrew huberman sleep

Jun 17, 2024

Andrew Huberman Supplements list for focus: Stanford Neuroscientist recommends

Award-winning neuroscientist Andrew Huberman recommended supplements including l-tyrosine & Alpha GPC. Find out why.
what is acetylcholine function acetylcholine supplements acetylcholine as a neurotransmitter

May 23, 2024

Guide to better memory: what is acetylcholine & what does it do for your brain

Wondering what acetylcholine is and how it can help your memory? Here's the ultimate guide to your memory and learning chemical, from function and brain role to deficiency and supplementation.
benefits of alpha gpc choline and omega 3 benefits

Oct 13, 2023

Benefits of Alpha GPC & DHA: Brain function at its best

Learn about the link between two powerful nutrients: choline and DHA. Discover how the two of them can work together to benefit cognitive development throughout life.
what foods contain alpha gpc alpha gpc natural sources foods rich in acetylcholine good source of choline natural sources of choline alpha gpc

Aug 14, 2023

Work smarter with natural sources of choline & Alpha GPC

Wondering how to work smarter? Learn more about your memory chemical acetylcholine and its building block choline Alpha GPC. Discover the natural sources of Alpha GPC.


Shopping Cart